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Anti-ARHGEF15 Polyclonal Antibody (HB586014)

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개요
카탈로그 번호HB586014
설명
Anti-ARHGEF15 Polyclonal Antibody (HB586014) is a rabbit polyclonal antibody detecting Rho guanine nucleotide exchange factor 15; Ephexin-5; E5; Vsm-RhoGEF; ARHGEF15; KIAA0915 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Human, Mouse
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant human ARHGEF15 (Arg619-Thr741).
타겟 Rho guanine nucleotide exchange factor 15; Ephexin-5; E5; Vsm-RhoGEF; ARHGEF15; KIAA0915
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 O94989, Q5FWH6
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Rho guanine nucleotide exchange factor 15 (ARHGEF15) is a ~91 kDa protein. Guanine nucleotide exchange factor (GEF) that activates RhoA, playing a role in the regulation of actin cytoskeleton organization. Is involved in the regulation of vascular smooth muscle contractility. Additionally, it negatively regulates excitatory synapse development by suppressing the synapse-promoting activity of EPHB2. Does not activate RAC1 or CDC42.

1. Ding, X. et al. (2023) Acta neuropathologica 145, 681-705. PMID: 36929019
2. Ogita, H. et al. (2003) Circulation research 93, 23-31. PMID: 12775584
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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