Anti-ARL6 Polyclonal Antibody (HA916014)

Name: Anti-ARL6 Polyclonal Antibody
Brand: abinScience
SKU: HA916014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA916014

설명

Anti-ARL6 Polyclonal Antibody (HA916014) is a rabbit polyclonal antibody detecting ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human ARL6 (Met1-Thr186).

타겟

ADP-ribosylation factor-like protein 6; Bardet-Biedl syndrome 3 protein; ARL6; BBS3

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q9H0F7, O88848, Q0IIM2, Q5M9P8

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

ADP-ribosylation factor-like protein 6 (ARL6) is a ~21 kDa protein. Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade.

1. Jin, H. et al. (2010) Cell 141, 1208-19. PMID: 20603001

2. Seo, S. et al. (2011) PLoS genetics 7, e1002358. PMID: 22072986

3. Wiens, CJ. et al. (2010) The Journal of biological chemistry 285, 16218-30. PMID: 20207729

참고사항

For research use only

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참고 문헌

데이터시트

Anti-ARL6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ARL6 Polyclonal Antibody (HA916014)

개요

이미지

참고 문헌

데이터시트

SDS