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| 카탈로그 번호 | HT090014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-ARNTL Polyclonal Antibody (HT090014) is a rabbit polyclonal antibody detecting ARNTL in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Equus caballus, and Chicken.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ARNTL (Glu48-Leu320). | ||||||||
| 타겟 | Basic-helix-loop-helix-PAS protein MOP3, ARNTL, Member of PAS protein 3, PAS domain-containing protein 3, BMAL1, Aryl hydrocarbon receptor nuclear translocator-like protein 1, BHLHE5, Class E basic helix-loop-helix protein 5, bHLHe5, MOP3, Brain and muscle ARNT-like 1, bHLH-PAS protein JAP3, PASD3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O00327 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Basic helix-loop-helix ARNT-like protein 1 (ARNTL) is a ~68 kDa protein. Transcriptional activator which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). 1. Wang, Z. et al. (2013) Cell research 23, 213-24. PMID: 23229515 2. Lin, R. et al. (2017) Molecular cell 68, 198-209.e6. PMID: 28985504 | ||||||||
| 참고사항 | For research use only. |
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