

| 카탈로그 번호 | VK023014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-ASFV D117L Polyclonal Antibody (VK023014) is a rabbit polyclonal antibody detecting ASFV D117L in ELISA, IHC, WB.
Highlights
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| 종 반응성 | African swine fever virus (ASFV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant ASFV D117L (Asp2-Thr38&Tyr60-Ser117). | ||||||||
| 타겟 | Minor capsid protein p17 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q89424 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Minor capsid protein p17 is a ~13 kDa protein. Together with the penton and the other minor capsid proteins (M1249L, p49), forms a complicated network immediately below the outer capsid shell, stabilizing the whole capsid. Three copies of p17 encircle each p72 capsomer in the inner capsid shell, anchoring p72 capsomers on the inner membrane. Required for the assembly of the capsid and icosahedral morphogenesis. Additionally, inhibits the host cGAS-STING pathway through its interaction with STING1 and subsequent interference of the recruitment of downstream components TBK1 and IKBKE. 1. Wang, N. et al. (2019) Science (New York, N.Y.) 366, 640-644. PMID: 31624094 2. Suárez, C. et al. (2010) Journal of virology 84, 7484-99. PMID: 20504920 3. Zheng, W. et al. (2022) Frontiers in immunology 13, 941579. PMID: 35844609 | ||||||||
| 참고사항 | For research use only |

Lane 1: recombinant ASFV D117L (Catalog No: VK023012)


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