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Anti-ASFV S273R Polyclonal Antibody (VK573014)

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개요
카탈로그 번호VK573014
설명
Anti-ASFV S273R Polyclonal Antibody (VK573014) is a rabbit polyclonal antibody detecting S273R in ELISA, IHC, WB.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성African swine fever virus (ASFV)
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant ASFV S273R (Met1-Ala273).
타겟 Cysteine protease S273R, pS273R, 3.4.22.-, Ba71V-111, S273R
정제 Purified by antigen affinity column.
등록번호 Q00946
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Cysteine protease S273R is a ~31 kDa protein. Cysteine protease that plays several role during infection including processing of the structural polyprotein or inhibition of the host immune response. Catalyzes the maturation of the pp220 and pp62 polyprotein precursors into core-shell proteins. Plays a role in the disruption of host pyroptosis via specific cleavage of gasdermin D/GSDMD. In addition, strongly decreases the host cGAS-STING signaling by targeting IKBKE via its enzymatic activity. Also impairs host FOXJ1-mediated antiviral effect via degradation of FOXJ1.

1. Andrés, G. et al. (2002) Journal of virology 76, 12473-82. PMID: 12438573
2. Zhao, G. et al. (2022) The Journal of biological chemistry 298, 101480. PMID: 34890644
3. Luo, J. et al. (2022) Virulence 13, 740-756. PMID: 35437104
4. Ma, C. et al. (2022) Virologica Sinica 37, 445-454. PMID: 35513267
5. Li, T. et al. (2023) The Journal of biological chemistry 299, 104844. PMID: 37209818
6. Li, YH. et al. (2023) Journal of virology 97, e0194222. PMID: 36856422
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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