

| 카탈로그 번호 | VK573014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-ASFV S273R Polyclonal Antibody (VK573014) is a rabbit polyclonal antibody detecting S273R in ELISA, IHC, WB.
Highlights
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| 종 반응성 | African swine fever virus (ASFV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant ASFV S273R (Met1-Ala273). | ||||||||
| 타겟 | Cysteine protease S273R, pS273R, 3.4.22.-, Ba71V-111, S273R | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q00946 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Cysteine protease S273R is a ~31 kDa protein. Cysteine protease that plays several role during infection including processing of the structural polyprotein or inhibition of the host immune response. Catalyzes the maturation of the pp220 and pp62 polyprotein precursors into core-shell proteins. Plays a role in the disruption of host pyroptosis via specific cleavage of gasdermin D/GSDMD. In addition, strongly decreases the host cGAS-STING signaling by targeting IKBKE via its enzymatic activity. Also impairs host FOXJ1-mediated antiviral effect via degradation of FOXJ1. 1. Andrés, G. et al. (2002) Journal of virology 76, 12473-82. PMID: 12438573 2. Zhao, G. et al. (2022) The Journal of biological chemistry 298, 101480. PMID: 34890644 3. Luo, J. et al. (2022) Virulence 13, 740-756. PMID: 35437104 4. Ma, C. et al. (2022) Virologica Sinica 37, 445-454. PMID: 35513267 5. Li, T. et al. (2023) The Journal of biological chemistry 299, 104844. PMID: 37209818 6. Li, YH. et al. (2023) Journal of virology 97, e0194222. PMID: 36856422 | ||||||||
| 참고사항 | For research use only. |
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