

| 카탈로그 번호 | HY455014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-ATP1A1 Polyclonal Antibody (HY455014) is a rabbit polyclonal antibody detecting ATP1A1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Anguilla anguilla.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human ATP1A1 (Thr347-Asp680). | ||||||||
| 타겟 | Na(+)/K(+) ATPase alpha-1 subunit, Sodium pump subunit alpha-1, Sodium/potassium-transporting ATPase subunit alpha-1, ATP1A1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P05023 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Sodium/potassium-transporting ATPase subunit alpha-1 (ATP1A1) is a ~112 kDa protein. This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Could also be part of an osmosensory signaling pathway that senses body-fluid sodium levels and controls salt intake behavior as well as voluntary water intake to regulate sodium homeostasis. 1. Lassuthova, P. et al. (2018) American journal of human genetics 102, 505-514. PMID: 29499166 2. Schlingmann, KP. et al. (2018) American journal of human genetics 103, 808-816. PMID: 30388404 | ||||||||
| 참고사항 | For research use only. |
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