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| 카탈로그 번호 | JN898023 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Bacillus anthracis | ||||
| 응용 분야 | ELISA, WB, SPR | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1, kappa | ||||
| 클론 ID | SAA1376 | ||||
| 타겟 | Protective antigen, PA, Anthrax toxins translocating protein, PA-83, PA83, Protective antigen PA-20, PA-20, PA20, Protective antigen PA-63, PA-63, PA63, pagA, pag, pXO1-110, BXA0164, GBAA_pXO1_0164 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P13423 | ||||
| RRID | Anti-Bacillus anthracis PA/pagA/PA-83 Antibody (SAA1376) (abinScience Cat# JN898023, RRID:AB_3726894) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Protective antigen (PA/pagA) is a ~85 kDa protein. Protective antigen constitutes one of the three proteins composing the anthrax toxin; it mediates attachment to host cells and translocation of edema factor (EF) and lethal factor (LF) into the host cytoplasm. PA associated with LF forms the lethal toxin (LeTx) and causes death when injected; PA associated with EF forms the edema toxin (EdTx) and produces edema. PA induces immunity to infection with anthrax. _x005F_x005F_x000D_ _x005F_x005F_x000D_1. Bradley, KA. et al. (2001) Nature 414, 225-9. PMID: 11700562 _x005F_x005F_x000D_
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2. Bradley, KA. et al. (2003) The Journal of biological chemistry 278, 49342-7. PMID: 14507921 _x005F_x005F_x000D_
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3. Santelli, E. et al. (2004) Nature 430, 905-8. PMID: 15243628 _x005F_x005F_x000D_
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4. Lacy, DB. et al. (2004) Proceedings of the National Academy of Sciences of the United States of America 101, 13147-51. PMID: 15326297 _x005F_x005F_x000D_
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5. Singh, Y. et al. (1991) The Journal of biological chemistry 266, 15493-7. PMID: 1651334 _x005F_x005F_x000D_
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6. Mock, M. et al. (2001) Annual review of microbiology 55, 647-71. PMID: 11544370 | ||||
| 참고사항 | For research use only. |
Detects Bacillus anthracis PA/pagA/PA-83 in indirect ELISAs.
SDS-PAGE for Anti-Bacillus anthracis PA/pagA/PA-83 Antibody (SAA1376).
Western blot analysis was performed using anti-Bacillus anthracis PA/pagA/PA-83 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Bacillus anthracis PA/pagA/PA-83 (Catalog No: JN898022)
Lane 2: negative control
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