

| 카탈로그 번호 | JN922014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Bacillus cereus gajA Polyclonal Antibody (JN922014) is a rabbit polyclonal antibody detecting gajA in ELISA, IHC, WB. Suitable for Bacillus cereus.
Highlights
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| 종 반응성 | Bacillus cereus | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Bacillus cereus gajA (Gly258-Gly578). | ||||||||
| 타겟 | Endonuclease GajA, 3.1.-.-, Gabija protein GajA, Nicking endonuclease GajA, gajA, IIE_04982 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | J8H9C1 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Endonuclease GajA is a ~66 kDa protein. Component of antiviral defense system Gabija type I, composed of GajA and GajB. Endonuclease that nicks double-stranded DNA within the sequence 5'-TNNNCGGGNNA-3' in the absence of nucleotides (NTP, dNTP and NDPs), cleaving after C-1. Has no detected ATPase activity. Expression of Gabija type I in B.subtilis (strain BEST7003) confers resistance to phages phi105, phi29, rho14, SpBeta and SBSphiC. Expression of Gabija type I in E.coli B (strain ATCC 11303) confers resistance to phage T7. 1. Doron, S. et al. (2018) Science (New York, N.Y.) 359. PMID: 29371424 2. Cheng, R. et al. (2021) Nucleic acids research 49, 5216-5229. PMID: 33885789 3. Antine, SP. et al. (2024) Nature 625, 360-365. PMID: 37992757 | ||||||||
| 참고사항 | For research use only. |
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