Anti-C1S Polyclonal Antibody (HY598014)

Name: Anti-C1S Polyclonal Antibody
Brand: abinScience
SKU: HY598014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HY598014

설명

Anti-C1S Polyclonal Antibody (HY598014) is a rabbit polyclonal antibody detecting C1S in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human C1S (Ile438-Pro685).

타겟

C1 esterase, Complement C1s subcomponent, C1S, Complement component 1 subcomponent s

정제

Purified by antigen affinity column.

등록번호

P09871

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Complement C1s subcomponent is a ~76 kDa protein. Component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. C1S is activated following association of the C1 complex with immunoglobulins (IgG or IgM) complexed with antigens to form antigen-antibody complexes on the surface of pathogens. C1S is cleaved and activated by C1R to generate C1s subcomponent heavy and light chains. C1s subcomponent light chain then cleaves and activates C2 and C4, the next components of the classical complement pathway.

1. Lacroix, M. et al. (2001) The Journal of biological chemistry 276, 36233-40. PMID: 11445589

2. Kerr, FK. et al. (2005) The Journal of biological chemistry 280, 39510-4. PMID: 16169853

3. Kerr, MA. et al. (1978) The Biochemical journal 171, 99-107. PMID: 417728

4. Reboul, A. et al. (1979) FEBS letters 103, 156-61. PMID: 467643

5. McRae, BJ. et al. (1981) The Journal of biological chemistry 256, 12362-6. PMID: 6271784

6. Thielens, NM. et al. (1982) FEBS letters 141, 19-24. PMID: 6282646

7. Thielens, NM. et al. (1984) FEBS letters 165, 111-6. PMID: 6319179

8. Nagasawa, S. et al. (1977) Proceedings of the National Academy of Sciences of the United States of America 74, 2998-3001. PMID: 70787

9. Rossi, V. et al. (1998) The Journal of biological chemistry 273, 1232-9. PMID: 9422791

10. Zwarthoff, SA. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34155115

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-C1S Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-C1S Polyclonal Antibody (HY598014)

개요

이미지

참고 문헌

데이터시트

SDS

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