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| 카탈로그 번호 | HS717014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-C2CD3 Polyclonal Antibody (HS717014) is a rabbit polyclonal antibody detecting C2CD3 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human C2CD3 (Asn1432-Leu1647). | ||||||||
| 타겟 | C2 domain-containing protein 3, C2CD3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q4AC94 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | C2 domain-containing protein 3 (C2CD3) is a ~260 kDa protein. Component of the centrioles that acts as a positive regulator of centriole elongation. Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation. Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3. 1. Thauvin-Robinet, C. et al. (2014) Nature genetics 46, 905-11. PMID: 24997988 2. Balestra, FR. et al. (2013) Developmental cell 25, 555-71. PMID: 23769972 | ||||||||
| 참고사항 | For research use only. |
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