Anti-C9 Polyclonal Antibody (HY033014)

Name: Anti-C9 Polyclonal Antibody
Brand: abinScience
SKU: HY033014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY033014

설명

Anti-C9 Polyclonal Antibody (HY033014) is a rabbit polyclonal antibody detecting C9 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human C9 (Gln22-His265).

타겟

Complement component C9, C9

정제

Purified by antigen affinity column.

등록번호

P02748

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Complement component C9 (Complement C9) is a ~63 kDa protein. Pore-forming component of the membrane attack complex (MAC), a multiprotein complex activated by the complement cascade, which inserts into a target cell membrane and forms a pore, leading to target cell membrane rupture and cell lysis. The MAC is initiated by proteolytic cleavage of C5 into complement C5b in response to the classical, alternative, lectin and GZMK complement pathways. The complement pathways consist in a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system. Constitutes the pore-forming subunit of the MAC complex: during MAC assembly, C9 associates with the C5b8 intermediate complex, and polymerizes to complete the pore.

1. Hadders, MA. et al. (2012) Cell reports 1, 200-7. PMID: 22832194

2. Serna, M. et al. (2016) Nature communications 7, 10587. PMID: 26841837

3. Dudkina, NV. et al. (2016) Nature communications 7, 10588. PMID: 26841934

4. Sharp, TH. et al. (2016) Cell reports 15, 1-8. PMID: 27052168

5. Menny, A. et al. (2018) Nature communications 9, 5316. PMID: 30552328

6. Podack, ER. et al. (1982) The Journal of experimental medicine 156, 268-82. PMID: 6177822

7. Lassiter, HA. et al. (1997) Pediatric research 42, 128-36. PMID: 9212048

8. Witzel-Schlömp, K. et al. (1998) Immunogenetics 48, 144-7. PMID: 9634479

9. Donado, CA. et al. (2025) Nature 641, 211-221. PMID: 39914456

10. Lan, F. et al. (2025) Nature 638, 490-498. PMID: 39814882

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-C9 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-C9 Polyclonal Antibody (HY033014)

개요

이미지

참고 문헌

데이터시트

SDS