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| 카탈로그 번호 | HB707014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CANX Polyclonal Antibody (HB707014) is a rabbit polyclonal antibody detecting CANX in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Pongo abelii.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CANX (His21-Pro481). | ||||||||
| 타겟 | Major histocompatibility complex class I antigen-binding protein p88, IP90, CANX, p90, Calnexin | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P27824 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Calnexin (CANX) is a ~67 kDa protein. Calcium-binding protein that interacts with newly synthesized monoglucosylated glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-CALNEXIN polyclonal antibody at 1ug/mL on various samples.
Lane 1: HepG2 cell lysate
Lane 2: K562 cell lysate
Lane 3: MCF-7 cell lysate
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