Anti-CASP14 Polyclonal Antibody (HB268014)

Name: Anti-CASP14 Polyclonal Antibody
Brand: abinScience
SKU: HB268014
Price: 168 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HB268014

설명

Anti-CASP14 Polyclonal Antibody (HB268014) is a rabbit polyclonal antibody detecting CASP14 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CASP14 (Met1-Gln242).

타겟

CASP14, CASP-14, Caspase-14

정제

Purified by antigen affinity column.

등록번호

P31944

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Caspase-14 (CASP14) is a ~27 kDa protein. Non-apoptotic caspase involved in epidermal differentiation. Is the predominant caspase in epidermal stratum corneum. Seems to play a role in keratinocyte differentiation and is required for cornification. Regulates maturation of the epidermis by proteolytically processing filaggrin. In vitro has a preference for the substrate [WY]-X-X-D motif and is active on the synthetic caspase substrate WEHD-ACF.

1. Fischer, H. et al. (2004) FEBS letters 577, 446-50. PMID: 15556625

2. Park, K. et al. (2006) Biochemical and biophysical research communications 347, 941-8. PMID: 16854378

3. Hibino, T. et al. (2010) Journal of cellular biochemistry 109, 487-97. PMID: 19960512

4. Beasley, S. et al. (2014) BioMed research international 2014, 417986. PMID: 25121097

5. Yamamoto-Tanaka, M. et al. (2014) Cell death & disease 5, e1181. PMID: 24743736

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-CASP14 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-CASP14 Polyclonal Antibody (HB268014)

개요

이미지

참고 문헌

데이터시트

SDS