

| 카탈로그 번호 | HV591014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CBY1 Polyclonal Antibody (HV591014) is a rabbit polyclonal antibody detecting CBY1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CBY1 (Lys12-Glu115). | ||||||||
| 타겟 | ARPP-binding protein, PGEA1, CBY1, Protein chibby homolog 1, ARB1, CBY, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, C22orf2, Cytosolic leucine-rich protein | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9Y3M2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Protein chibby homolog 1 (CBY1) is a ~14 kDa protein. Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. 1. Takemaru, K. et al. (2003) Nature 422, 905-9. PMID: 12712206 2. Mofunanya, A. et al. (2009) BMC molecular biology 10, 41. PMID: 19435523 3. Hidaka, S. et al. (2004) The Journal of biological chemistry 279, 35009-16. PMID: 15194699 | ||||||||
| 참고사항 | For research use only. |
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