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| 카탈로그 번호 | HV164014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CC2D1A (Pro675-Ser944). | ||||||||
| 타겟 | AKI1, Five prime repressor element under dual repression-binding protein 1, Akt kinase-interacting protein 1, Freud-1, Coiled-coil and C2 domain-containing protein 1A, FRE under dual repression-binding protein 1, Putative NF-kappa-B-activating protein 023N, CC2D1A | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q6P1N0 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Coiled-coil and C2 domain-containing protein 1A (CC2D1A) is a ~104 kDa protein. Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses. | ||||||||
| 참고사항 | For research use only. |
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