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| 카탈로그 번호 | HV191014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CD180 Polyclonal Antibody (HV191014) is a rabbit polyclonal antibody detecting CD180 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CD180 (Thr430-Gly626). | ||||||||
| 타겟 | Radioprotective 105 kDa protein, Lymphocyte antigen 64, RP105, LY64, CD180 antigen, CD180 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q99467 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | CD180 antigen is a ~74 kDa protein. Pattern recognition receptor predominantly expressed on B-cells, dendritic cells, and certain monocytes/macrophages, structurally resembling Toll-like receptors (TLRs) that plays a role in modulating immune responses. While ressembling a TLR, lacks the intracellular TIR (Toll/IL-1R) signaling domain and thus does not directly transduce signals. Instead, modulates immune responses, often in conjunction with other TLRs. For example, in cooperation with MD-1/LY86, interacts directly with the TLR4 signaling complex, inhibiting its ability to bind microbial ligand. 1. Divanovic, S. et al. (2005) Nature immunology 6, 571-8. PMID: 15852007 | ||||||||
| 참고사항 | For research use only. |
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