

| 카탈로그 번호 | HF719014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CD218b/IL18RAP Polyclonal Antibody (HF719014) is a rabbit polyclonal antibody detecting IL18RAP in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CD218b/IL18RAP (Phe20-Arg356). | ||||||||
| 타겟 | AcPL, Accessory protein-like, Interleukin-1 receptor 7, IL-18R-beta, CD218 antigen-like family member B, IL-1RAcPL, Interleukin-18 receptor accessory protein, CDw218b, IL-1R-7, IL1R7, IL-1R7, IL-18RAcP, CD218b, IL-1R accessory protein-like, IL18RAP, Interleukin-18 receptor accessory protein-like, IL-18 receptor accessory protein, IL-18Rbeta, Interleukin-18 receptor beta | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O95256 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Interleukin-18 receptor accessory protein (CD218b/IL18RAP) is a ~68 kDa protein. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable). 1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293 2. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532 3. Born, TL. et al. (1998) The Journal of biological chemistry 273, 29445-50. PMID: 9792649 | ||||||||
| 참고사항 | For research use only. |
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