

| 카탈로그 번호 | HV190014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CD280/MRC2 Polyclonal Antibody (HV190014) is a rabbit polyclonal antibody detecting CD280 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CD280/MRC2 (Pro41-Lys505). | ||||||||
| 타겟 | Urokinase receptor-associated protein, MRC2, CD280, Endocytic receptor 180, KIAA0709, C-type lectin domain family 13 member E, CLEC13E, UPARAP, ENDO180, UPAR-associated protein, C-type mannose receptor 2, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9UBG0 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | C-type mannose receptor 2 (CD280/MRC2) is a ~166 kDa protein. May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. | ||||||||
| 참고사항 | For research use only. |
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