Anti-CDC42 Polyclonal Antibody (HX069014)

Name: Anti-CDC42 Polyclonal Antibody
Brand: abinScience
SKU: HX069014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HX069014

설명

Anti-CDC42 Polyclonal Antibody (HX069014) is a rabbit polyclonal antibody detecting CDC42 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Aedes aegypti.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CDC42 (Met1-Cys188).

타겟

CDC42, G25K GTP-binding protein, Cell division control protein 42 homolog

정제

Purified by antigen affinity column.

등록번호

P60953

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Cell division control protein 42 homolog (CDC42) is a ~21 kDa protein. Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration.

1. Oceguera-Yanez, F. et al. (2005) The Journal of cell biology 168, 221-32. PMID: 15642749

2. Modzelewska, K. et al. (2006) The Journal of biological chemistry 281, 37527-35. PMID: 17038317

3. Hong, IK. et al. (2012) The Journal of biological chemistry 287, 32027-39. PMID: 22843693

4. Gauthier-Campbell, C. et al. (2004) Molecular biology of the cell 15, 2205-17. PMID: 14978216

5. Majmundar, AJ. et al. (2021) Science advances 7. PMID: 33523862

6. Schlam, D. et al. (2015) Nature communications 6, 8623. PMID: 26465210

7. Ninomiya, K. et al. (2021) Journal of cell science 134. PMID: 33310911

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-CDC42 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-CDC42 Polyclonal Antibody (HX069014)

개요

이미지

참고 문헌

데이터시트

SDS