

| 카탈로그 번호 | HB436014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CDC73 Polyclonal Antibody (HB436014) is a rabbit polyclonal antibody detecting Parafibromin; Cell division cycle protein 73 homolog; Hyperparathyroidism 2 protein; CDC73; C1orf28; HRPT2 in ELISA, IHC, WB. Suitable for Mouse, Rat, Human, and Chicken.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human CDC73 (Gly356-Phe531). | ||||||||
| 타겟 | Parafibromin; Cell division cycle protein 73 homolog; Hyperparathyroidism 2 protein; CDC73; C1orf28; HRPT2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8JZM7, Q4V8C8, Q6P1J9, Q5ZLM0 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Parafibromin (CDC73) is a ~60 kDa protein. Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression. Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II and is implicated in regulation of development and maintenance of embryonic stem cell pluripotency. PAF1C associates with RNA polymerase II through interaction with POLR2A CTD non-phosphorylated and 'Ser-2'- and 'Ser-5'-phosphorylated forms and is involved in transcriptional elongation, acting both independently and synergistically with TCEA1 and in cooperation with the DSIF complex and HTATSF1. PAF1C is required for transcription of Hox and Wnt target genes. | ||||||||
| 참고사항 | For research use only |
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