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Anti-CDK10 Polyclonal Antibody (HB532014)

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개요
카탈로그 번호HB532014
설명
Anti-CDK10 Polyclonal Antibody (HB532014) is a rabbit polyclonal antibody detecting Cyclin-dependent kinase 10; 2.7.11.22; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE; CDK10 in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, and Bovine.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human, Mouse, Rat
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant human CDK10 (Met1-Pro360).
타겟 Cyclin-dependent kinase 10; 2.7.11.22; Cell division protein kinase 10; Serine/threonine-protein kinase PISSLRE; CDK10
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 Q15131, Q4KM47, Q3UMM4, Q2TBL8
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Cyclin-dependent kinase 10 (CDK10) is a ~41 kDa protein. Cyclin-dependent kinase that phosphorylates the transcription factor ETS2 (in vitro) and positively controls its proteasomal degradation (in cells). Involved in the regulation of actin cytoskeleton organization through the phosphorylation of actin dynamics regulators such as PKN2. Is a negative regulator of ciliogenesis through phosphorylation of PKN2 and promotion of RhoA signaling.

1. Guen, VJ. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 19525-30. PMID: 24218572
2. Guen, VJ. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 678-88. PMID: 27104747
참고사항 For research use only
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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