

| 카탈로그 번호 | HW830014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CDKN1B Polyclonal Antibody (HW830014) is a rabbit polyclonal antibody detecting CDKN1B in ELISA, IHC, WB. Suitable for Dog, Cricetulus griseus, Cat, Human, and Mouse.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CDKN1B (Met1-Thr198). | ||||||||
| 타겟 | Cyclin-dependent kinase inhibitor 1B, KIP1, CDKN1B, p27Kip1, Cyclin-dependent kinase inhibitor p27 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P46527 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a ~22 kDa protein. Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation. 1. McGrath, DA. et al. (2017) The EMBO journal 36, 2251-2262. PMID: 28666995 | ||||||||
| 참고사항 | For research use only. |
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