Anti-CEBPA Polyclonal Antibody (HW834024)

Name: Anti-CEBPA Polyclonal Antibody
Brand: abinScience
SKU: HW834024
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HW834024

설명

Anti-CEBPA Polyclonal Antibody (HW834024) is a rabbit polyclonal antibody detecting CCAAT/enhancer-binding protein alpha; C/EBP alpha; CEBPA; CEBP in ELISA, IHC, WB. Suitable for Mouse, Bovine, Rat, and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human CEBPA (Asn281-Ala358).

타겟

CCAAT/enhancer-binding protein alpha; C/EBP alpha; CEBPA; CEBP

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P53566, O02754, P05554, P49715

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

CCAAT/enhancer-binding protein alpha (CEBPA) is a ~37 kDa protein. Transcription factor that coordinates proliferation arrest and the differentiation of myeloid progenitors, adipocytes, hepatocytes, and cells of the lung and the placenta. Binds directly to the consensus DNA sequence 5'-T[TG]NNGNAA[TG]-3' acting as an activator on distinct target genes. During early embryogenesis, plays essential and redundant functions with CEBPB. Essential for the transition from common myeloid progenitors (CMP) to granulocyte/monocyte progenitors (GMP). Critical for the proper development of the liver and the lung.

1. Wang, GL. et al. (2004) Genes & development 18, 912-25. PMID: 15107404

2. Zhang, P. et al. (2004) Immunity 21, 853-63. PMID: 15589173

3. Zhang, Z. et al. (2022) Cell metabolism 34, 1860-1874.e4. PMID: 36228616

4. Lin, FT. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 9606-10. PMID: 8415748

5. Bégay, V. et al. (2004) Molecular and cellular biology 24, 9744-51. PMID: 15509779

6. Ohlsson, E. et al. (2014) The Journal of experimental medicine 211, 5-13. PMID: 24367003

7. Flodby, P. et al. (1996) The Journal of biological chemistry 271, 24753-60. PMID: 8798745

8. Samuelsson, L. et al. (1991) The EMBO journal 10, 3787-93. PMID: 1935900

9. Lin, FT. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 8757-61. PMID: 8090719

10. Porse, BT. et al. (2001) Cell 107, 247-58. PMID: 11672531

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-CEBPA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-CEBPA Polyclonal Antibody (HW834024)

개요

이미지

참고 문헌

데이터시트

SDS

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