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| 카탈로그 번호 | AF004014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Cetuximab Polyclonal Antibody (AF004014) is a rabbit polyclonal antibody detecting Cetuximab in ELISA.
Highlights
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| 종 반응성 | General | ||||||||
| 응용 분야 | ELISA | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | Cetuximab | ||||||||
| 타겟 | Rabbit polyclonal to Erbitux. | ||||||||
| 특이성 | The product is specific for Cetuximab. This antibody serves as an excellent positive control for Cetuximab immunogenicity (ADA) assays. | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >90% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | CAS: 205923-56-4 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Cetuximab (Erbitux) is a chimeric (mouse/human) monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with metastatic colorectal cancer, metastatic non-small cell lung cancer and head and neck cancer. Cetuximab, as an epidermal growth factor receptor (EGFR) inhibitor, binds to EGFR. • Polyclonal antibody-induced downregulation of HER1/EGFR and HER2 surpasses the effect of combinations of specific registered antibodies., PMID:36408164 • Polyclonal antitumor immunoglobulin may play a role in ovarian cancer adjuvant therapy., PMID:21255939 | ||||||||
| 참고사항 | For research use only. |
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