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| 카탈로그 번호 | VK535014 | ||||||||
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| 설명 |
Anti-CHPV M/Matrix protein Polyclonal Antibody (VK535014) is a rabbit polyclonal antibody detecting Matrix protein in ELISA, IHC, WB.
Highlights
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| 종 반응성 | Chandipura virus (CHPV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Chandipura virus (CHPV) M/Matrix protein (Phe47-His229). | ||||||||
| 타겟 | Matrix protein, M | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9WH76 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Matrix protein is a ~26 kDa protein. Forms a double layer around the helical nucleocapsid, the inner matrix layer binding to the N helix and the outer matrix layer binding to the envelope glycoprotein. Plays a major role in assembly and budding of virion, by recruiting cellular partners of the ESCRT complexes that play a key role in releasing the budding particle from the host membrane. Condensates the ribonucleocapsid core during virus assembly. Inhibits the host mRNA nuclear export thereby inducing the shut off of cellular transcription and preventing the interferon signaling and the establishment of antiviral state in infected cells. This shutoff presumably inhibits interferon signaling and thus establishment of antiviral state in virus infected cells. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-Matrix-CHPV polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant CHPV M/Matrix protein (Catalog No: VK535012)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
