Anti-CHRNA2 Polyclonal Antibody (HA818014)

Name: Anti-CHRNA2 Polyclonal Antibody
Brand: abinScience
SKU: HA818014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HA818014

설명

Anti-CHRNA2 Polyclonal Antibody (HA818014) is a rabbit polyclonal antibody detecting Neuronal acetylcholine receptor subunit alpha-2; CHRNA2 in ELISA, IHC, WB. Suitable for Human, Rat, Mouse, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human CHRNA2 (Glu27-Pro265).

타겟

Neuronal acetylcholine receptor subunit alpha-2; CHRNA2

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q15822, P12389, Q91X60, P09480

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Neuronal acetylcholine receptor subunit alpha-2 (CHRNA2) is a ~59 kDa protein. Component of neuronal acetylcholine receptors (nAChRs) that function as pentameric, ligand-gated cation channels with high calcium permeability among other activities. nAChRs are excitatory neurotrasnmitter receptors formed by a collection of nAChR subunits known to mediate synaptic transmission in the nervous system and the neuromuscular junction. Each nAchR subunit confers differential attributes to channel properties, including activation, deactivation and desensitization kinetics, pH sensitivity, cation permeability, and binding to allosteric modulators. CHRNA2 forms heteropentameric neuronal acetylcholine receptors with CHRNB2 and CHRNB4 and plays a role in nicotine dependence.

1. Millar, NS. et al. (2009) Neuropharmacology 56, 237-46. PMID: 18723036

2. Dash, B. et al. (2014) Neuropharmacology 79, 715-25. PMID: 24467848

3. Kouvatsos, N. et al. (2016) Proceedings of the National Academy of Sciences of the United States of America 113, 9635-40. PMID: 27493220

참고사항

For research use only

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참고 문헌

데이터시트

Anti-CHRNA2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-CHRNA2 Polyclonal Antibody (HA818014)

개요

이미지

참고 문헌

데이터시트

SDS

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