

| 카탈로그 번호 | HT459014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CLIC1 Polyclonal Antibody (HT459014) is a rabbit polyclonal antibody detecting CLIC1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CLIC1 (Lys79-Lys241). | ||||||||
| 타겟 | Regulatory nuclear chloride ion channel protein, CLIC1, NCC27, Nuclear chloride ion channel 27, Chloride channel ABP, Chloride intracellular channel protein 1, hRNCC, G6 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O00299 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Chloride intracellular channel protein 1 (CLIC1) is a ~26 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduces selenite and dehydroascorbate and may act as an antioxidant during oxidative stress response. Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Involved in regulation of the cell cycle. 1. Al Khamici, H. et al. (2015) PloS one 10, e115699. PMID: 25581026 2. Alghalayini, A. et al. (2023) Biomolecules 13. PMID: 37759794 | ||||||||
| 참고사항 | For research use only. |
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