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| 카탈로그 번호 | HY099014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-CTSL Polyclonal Antibody (HY099014) is a rabbit polyclonal antibody detecting CTSL in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human CTSL (Ala114-Thr288). | ||||||||
| 타겟 | CTSL1, MEP, Procathepsin L, Major excreted protein, Cathepsin L1, CTSL | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P07711 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Procathepsin L (CTSL) is a ~37 kDa protein. Thiol protease important for the overall degradation of proteins in lysosomes (Probable). Plays a critical for normal cellular functions such as general protein turnover, antigen processing and bone remodeling. Involved in the solubilization of cross-linked TG/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen. In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin peptide neurotransmitter. In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound peptide ligands presented by cortical thymic epithelial cells. 1. Felbor, U. et al. (2000) The EMBO journal 19, 1187-94. PMID: 10716919 | ||||||||
| 참고사항 | For research use only. |
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