Anti-CUBN Polyclonal Antibody (HT153014)

Name: Anti-CUBN Polyclonal Antibody
Brand: abinScience
SKU: HT153014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HT153014

설명

Anti-CUBN Polyclonal Antibody (HT153014) is a rabbit polyclonal antibody detecting CUBN in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CUBN (Cys3511-Ser3623).

타겟

Cubilin, 460 kDa receptor, Intrinsic factor-vitamin B12 receptor, IFCR, Intestinal intrinsic factor receptor, Intrinsic factor-cobalamin receptor, CUBN

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O60494

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Cubilin (CUBN) is a ~398 kDa protein. Endocytic receptor which plays a role in lipoprotein, vitamin and iron metabolism by facilitating their uptake. Acts together with LRP2 to mediate endocytosis of high-density lipoproteins, GC, hemoglobin, ALB, TF and SCGB1A1. Acts together with AMN to mediate endocytosis of the CBLIF-cobalamin complex. Binds to ALB, MB, Kappa and lambda-light chains, TF, hemoglobin, GC, SCGB1A1, APOA1, high density lipoprotein, and the CBLIF-cobalamin complex. Ligand binding requires calcium.

1. Kozyraki, R. et al. (1999) Nature medicine 5, 656-61. PMID: 10371504

2. Kozyraki, R. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 12491-6. PMID: 11606717

3. Nykjaer, A. et al. (2001) Proceedings of the National Academy of Sciences of the United States of America 98, 13895-900. PMID: 11717447

4. Fyfe, JC. et al. (2004) Blood 103, 1573-9. PMID: 14576052

5. Kozyraki, R. et al. (1998) Blood 91, 3593-600. PMID: 9572993

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-CUBN Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-CUBN Polyclonal Antibody (HT153014)

개요

이미지

참고 문헌

데이터시트

SDS