Anti-CYGB Polyclonal Antibody (HV972024)

Name: Anti-CYGB Polyclonal Antibody
Brand: abinScience
SKU: HV972024
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HV972024

설명

Anti-CYGB Polyclonal Antibody (HV972024) is a rabbit polyclonal antibody detecting CYGB in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human CYGB (Met1-Lys111).

타겟

Histoglobin, CYGB, Stellate cell activation-associated protein, Cytoglobin, STAP, HGb

정제

Purified by antigen affinity column.

등록번호

Q8WWM9

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Cytoglobin (CYGB) is a ~21 kDa protein. Probable multifunctional globin with a hexacoordinated heme iron required for the catalysis of various reactions depending on redox condition of the cell as well as oxygen availability. Has a nitric oxide dioxygenase (NOD) activity and is most probably involved in cell-mediated and oxygen-dependent nitric oxide consumption. By scavenging this second messenger may regulate several biological processes including endothelium-mediated vasodilation and vascular tone. Under normoxic conditions functions as a nitric oxide dioxygenase (NOD) but under hypoxic conditions the globin may switch its function to that of a nitrite (NO2) reductase (NiR), generating nitric oxide. Could also have peroxidase and superoxide dismutase activities, detoxifying reactive oxygen species and protecting cells against oxidative stress.

1. Trent, JT. et al. (2002) The Journal of biological chemistry 277, 19538-45. PMID: 11893755

2. Asahina, K. et al. (2002) Biochimica et biophysica acta 1577, 471-5. PMID: 12359339

3. Sugimoto, H. et al. (2004) Journal of molecular biology 339, 873-85. PMID: 15165856

4. Halligan, KE. et al. (2009) The Journal of biological chemistry 284, 8539-47. PMID: 19147491

5. Gardner, AM. et al. (2010) The Journal of biological chemistry 285, 23850-7. PMID: 20511233

6. Liu, X. et al. (2017) Nature communications 8, 14807. PMID: 28393874

7. Amdahl, MB. et al. (2017) Biochemistry 56, 3993-4004. PMID: 28671819

8. Reeder, BJ. et al. (2018) Nitric oxide : biology and chemistry 72, 16-23. PMID: 29128400

9. Dat, NQ. et al. (2021) Hepatology (Baltimore, Md.) 73, 2527-2545. PMID: 33576020

10. Zweier, JL. et al. (2021) Proceedings of the National Academy of Sciences of the United States of America 118. PMID: 34930834

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-CYGB Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-CYGB Polyclonal Antibody (HV972024)

개요

이미지

참고 문헌

데이터시트

SDS