

| 카탈로그 번호 | HA684014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-DAP Polyclonal Antibody (HA684014) is a rabbit polyclonal antibody detecting Death-associated protein 1; DAP-1; DAP; DAP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, and Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human DAP (Ser2-Lys102). | ||||||||
| 타겟 | Death-associated protein 1; DAP-1; DAP; DAP1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P51397, Q91XC8, Q5EAE6, Q9QX67 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Death-associated protein 1 (DAP) is a ~11 kDa protein. Ribosome-binding protein involved in ribosome hibernation, a process during which ribosomes are stabilized in an inactive state and preserved from proteasomal degradation. Acts via its association with eiF5a (EIF5A and EIF5A2) at the polypeptide exit tunnel of the ribosome, preventing mRNA translation. Involved in ribosome hibernation in the mature oocyte by preventing mRNA translation, leading to ribosome inactivation. Ribosomes, which are produced in large quantities during oogenesis, are stored and translationally repressed in the oocyte and early embryo. Also acts as a negative regulator of autophagy. 1. Koren, I. et al. (2010) Current biology : CB 20, 1093-8. PMID: 20537536 2. Deiss, LP. et al. (1995) Genes & development 9, 15-30. PMID: 7828849 | ||||||||
| 참고사항 | For research use only |
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