Anti-DCAF15 Polyclonal Antibody (HB522014)

Name: Anti-DCAF15 Polyclonal Antibody
Brand: abinScience
SKU: HB522014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB522014

설명

Anti-DCAF15 Polyclonal Antibody (HB522014) is a rabbit polyclonal antibody detecting DDB1- and CUL4-associated factor 15; DCAF15; C19orf72 in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Frog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human DCAF15 (Tyr386-Val564).

타겟

DDB1- and CUL4-associated factor 15; DCAF15; C19orf72

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q66K64, Q3SZD5, Q6PFH3, A2BDA5

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

DDB1- and CUL4-associated factor 15 (DCAF15) is a ~66 kDa protein. Substrate-recognition component of the DCX(DCAF15) complex, a cullin-4-RING E3 ubiquitin-protein ligase complex that mediates ubiquitination and degradation of target proteins. The DCX(DCAF15) complex acts as a regulator of the natural killer (NK) cells effector functions, possibly by mediating ubiquitination and degradation of cohesin subunits SMC1A and SMC3. May play a role in the activation of antigen-presenting cells (APC) and their interaction with NK cells.

1. Jin, J. et al. (2006) Molecular cell 23, 709-21. PMID: 16949367

2. Pech, MF. et al. (2019) eLife 8. PMID: 31452512

참고사항

For research use only

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참고 문헌

데이터시트

Anti-DCAF15 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-DCAF15 Polyclonal Antibody (HB522014)

개요

이미지

참고 문헌

데이터시트

SDS

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