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| 카탈로그 번호 | HX130014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-DCD Polyclonal Antibody (HX130014) is a rabbit polyclonal antibody detecting DCD in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DCD (Cys18-Leu110). | ||||||||
| 타겟 | DCD, AIDD, DSEP, Dermcidin, Preproteolysin | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P81605 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Dermcidin (DCD) is a ~11 kDa protein. Found in sweat, has an antimicrobial activity during early bacterial colonization. The secreted peptide assembles into homohexameric complexes that can associate with and also insert into pathogen membranes. Once inserted in bacteria membranes forms anion channels probably altering the transmembrane potential essential for bacterial survival. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. 1. Schittek, B. et al. (2001) Nature immunology 2, 1133-7. PMID: 11694882 2. Song, C. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, 4586-91. PMID: 23426625 3. Lee Motoyama, JP. et al. (2007) Biochemical and biophysical research communications 357, 828-33. PMID: 17448443 | ||||||||
| 참고사항 | For research use only. |
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