Anti-DDX6 Polyclonal Antibody (HA609014)

Name: Anti-DDX6 Polyclonal Antibody
Brand: abinScience
SKU: HA609014
Price: 96 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HA609014

설명

Anti-DDX6 Polyclonal Antibody (HA609014) is a rabbit polyclonal antibody detecting Probable ATP-dependent RNA helicase DDX6; 3.6.4.13; ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK; DDX6; HLR2; RCK in ELISA, IHC, WB. Suitable for Human, Chicken, Mouse, and Frog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human DDX6 (Glu97-Pro483).

타겟

Probable ATP-dependent RNA helicase DDX6; 3.6.4.13; ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK; DDX6; HLR2; RCK

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P26196, Q5ZKB9, P54823, P54824

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Probable ATP-dependent RNA helicase DDX6 is a ~54 kDa protein. Essential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions. Plays a role in P-bodies to coordinate the storage of translationally inactive mRNAs in the cytoplasm and prevent their degradation. In the process of mRNA degradation, plays a role in mRNA decapping. Blocks autophagy in nutrient-rich conditions by repressing the expression of ATG-related genes through degradation of their transcripts.

1. Ayache, J. et al. (2015) Molecular biology of the cell 26, 2579-95. PMID: 25995375

2. Kamenska, A. et al. (2016) Nucleic acids research 44, 6318-34. PMID: 27342281

3. Balak, C. et al. (2019) American journal of human genetics 105, 509-525. PMID: 31422817

4. Fenger-Grøn, M. et al. (2005) Molecular cell 20, 905-15. PMID: 16364915

5. Hu, G. et al. (2015) Nature cell biology 17, 930-942. PMID: 26098573

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-DDX6 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-DDX6 Polyclonal Antibody (HA609014)

개요

이미지

참고 문헌

데이터시트

SDS