Anti-DEFA3 Polyclonal Antibody (HX987014)

Name: Anti-DEFA3 Polyclonal Antibody
Brand: abinScience
SKU: HX987014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HX987014

설명

Anti-DEFA3 Polyclonal Antibody (HX987014) is a rabbit polyclonal antibody detecting DEFA3 in ELISA, IHC, WB. Suitable for Human, Macaca mulatta, Pan troglodytes, and Papio hamadryas.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human DEFA3 (Pro21-Cys94).

타겟

HP3, Neutrophil defensin 3, HNP-3, HNP-2, DEF3, HP-3, Defensin, alpha 3, DEFA3, HP-2, HP2

정제

Purified by antigen affinity column.

등록번호

P59666

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Neutrophil defensin 3 (DEFA3) is a ~10 kDa protein. Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B.anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Also blocks herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment.

1. Ericksen, B. et al. (2005) Antimicrobial agents and chemotherapy 49, 269-75. PMID: 15616305

2. Kim, C. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 4830-5. PMID: 15772169

3. Hazrati, E. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 8658-66. PMID: 17142766

4. Giesemann, T. et al. (2008) Gastroenterology 134, 2049-58. PMID: 18435932

5. Cardot-Martin, E. et al. (2015) Letters in applied microbiology 61, 158-64. PMID: 25963798

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-DEFA3 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-DEFA3 Polyclonal Antibody (HX987014)

개요

이미지

참고 문헌

데이터시트

SDS