Anti-DGKQ Polyclonal Antibody (HW435014)

Name: Anti-DGKQ Polyclonal Antibody
Brand: abinScience
SKU: HW435014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HW435014

설명

Anti-DGKQ Polyclonal Antibody (HW435014) is a rabbit polyclonal antibody detecting DGKQ in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human DGKQ (Pro584-Ala721).

타겟

DGKQ, Diglyceride kinase theta, DGK-theta, DAG kinase theta, DGKtheta, DAGK4, Diacylglycerol kinase theta

정제

Purified by antigen affinity column.

등록번호

P52824

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Diacylglycerol kinase theta (DGKQ) is a ~101 kDa protein. Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Within the adrenocorticotropic hormone signaling pathway, produces phosphatidic acid which in turn activates NR5A1 and subsequent steroidogenic gene transcription. Also functions downstream of the nerve growth factor signaling pathway being specifically activated in the nucleus by the growth factor. Through its diacylglycerol activity also regulates synaptic vesicle endocytosis.

1. Bregoli, L. et al. (2001) The Journal of biological chemistry 276, 23288-95. PMID: 11309392

2. Gellett, AM. et al. (2012) Biochemical and biophysical research communications 422, 758-63. PMID: 22627129

3. Houssa, B. et al. (1997) The Journal of biological chemistry 272, 10422-8. PMID: 9099683

4. Li, D. et al. (2007) Molecular and cellular biology 27, 6669-85. PMID: 17664281

5. Goldschmidt, HL. et al. (2016) Cell reports 14, 200-7. PMID: 26748701

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-DGKQ Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-DGKQ Polyclonal Antibody (HW435014)

개요

이미지

참고 문헌

데이터시트

SDS