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| 카탈로그 번호 | HV780014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-DKK2 Polyclonal Antibody (HV780014) is a rabbit polyclonal antibody detecting DKK2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DKK2 (Lys34-Ile259). | ||||||||
| 타겟 | Dkk-2, hDkk-2, Dickkopf-related protein 2, DKK2, Dickkopf-2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9UBU2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Dickkopf-related protein 2 (DKK2) is a ~28 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. | ||||||||
| 참고사항 | For research use only. |
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