

| 카탈로그 번호 | HB712014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-DNASE1 Polyclonal Antibody (HB712014) is a rabbit polyclonal antibody detecting DNASE1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DNASE1 (Gly19-Ala259). | ||||||||
| 타겟 | DNL1, Deoxyribonuclease I, DNASE1, Dornase alfa, Deoxyribonuclease-1, DNase I, DRNI | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P24855 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Deoxyribonuclease-1 (DNASE1) is a ~31 kDa protein. Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA. Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization. Together with DNASE1L3, plays a key role in degrading neutrophil extracellular traps (NETs). 1. Oliveri, M. et al. (2001) European journal of immunology 31, 743-51. PMID: 11241278 2. Shak, S. et al. (1990) Proceedings of the National Academy of Sciences of the United States of America 87, 9188-92. PMID: 2251263 3. Yasuda, T. et al. (1990) Journal of biochemistry 108, 393-8. PMID: 2277032 | ||||||||
| 참고사항 | For research use only. |
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