

| 카탈로그 번호 | HS757014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-DUSP6 Polyclonal Antibody (HS757014) is a rabbit polyclonal antibody detecting DUSP6 in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human DUSP6 (Met1-Leu347). | ||||||||
| 타겟 | Mitogen-activated protein kinase phosphatase 3, MKP3, DUSP6, PYST1, MAP kinase phosphatase 3, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, MKP-3 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q16828 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Dual specificity protein phosphatase 6 (DUSP6) is a ~42 kDa protein. Dual specificity protein phosphatase, which mediates dephosphorylation and inactivation of MAP kinases. Has a specificity for the ERK family. Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain. 1. Groom, LA. et al. (1996) The EMBO journal 15, 3621-32. PMID: 8670865 2. Mishra, A. et al. (2017) eLife 6. PMID: 29043977 | ||||||||
| 참고사항 | For research use only. |
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