Anti-DVL2 Polyclonal Antibody (HT483024)

Name: Anti-DVL2 Polyclonal Antibody
Brand: abinScience
SKU: HT483024
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HT483024

설명

Anti-DVL2 Polyclonal Antibody (HT483024) is a rabbit polyclonal antibody detecting DVL2 in ELISA, IHC, WB. Suitable for Human, Mouse, Xenopus laevis, and Xenopus tropicalis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human DVL2 (Asn264-Lys353).

타겟

Dishevelled-2, DVL2, DSH homolog 2, Segment polarity protein dishevelled homolog DVL-2

정제

Purified by antigen affinity column.

등록번호

O14641

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Segment polarity protein dishevelled homolog DVL-2 (DVL2) is a ~78 kDa protein. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.

1. Geng, Y. et al. (2014) The Journal of biological chemistry 289, 11230-11241. PMID: 24616100

참고사항

For research use only.

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