

| 카탈로그 번호 | JN912014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-E. coli groES Polyclonal Antibody (JN912014) is a rabbit polyclonal antibody detecting groES. Suitable for strain K12.
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| 종 반응성 | Escherichia coli | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant E. coli groES (Met1-Ala97). | ||||||||
| 타겟 | 10 kDa chaperonin, Chaperonin-10, Co-chaperonin GroES, Cpn10, groES, groS, mopB | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P0A6F9 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Co-chaperonin GroES is a ~10 kDa protein. Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding, probably by preventing aggregation and by entropically destabilizing folding intermediates. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel. Regulates the ATPase activity of GroEL. 1. Goloubinoff, P. et al. (1989) Nature 342, 884-9. PMID: 10532860 2. Tang, YC. et al. (2006) Cell 125, 903-14. PMID: 16751100 3. Martin, J. et al. (1991) Nature 352, 36-42. PMID: 1676490 4. Tang, YC. et al. (2008) The EMBO journal 27, 1458-68. PMID: 18418386 5. Apetri, AC. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 17351-5. PMID: 18987317 6. Chakraborty, K. et al. (2010) Cell 142, 112-22. PMID: 20603018 7. Gupta, AJ. et al. (2014) Journal of molecular biology 426, 2739-54. PMID: 24816391 8. Kusukawa, N. et al. (1989) The EMBO journal 8, 3517-21. PMID: 2573517 9. Hemmingsen, SM. et al. (1988) Nature 333, 330-4. PMID: 2897629 | ||||||||
| 참고사항 | For research use only |
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