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| 카탈로그 번호 | HP762014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human EARS2 (Gly247-Gln496). | ||||||||
| 타겟 | KIAA1970, Glutamyl-tRNA synthetase, EARS2, Probable glutamate--tRNA ligase, mitochondrial, GluRS | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q5JPH6 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Nondiscriminating glutamyl-tRNA synthetase EARS2, mitochondrial is a ~58 kDa protein. Non-discriminating glutamyl-tRNA synthetase that catalyzes aminoacylation of both mitochondrial tRNA(Glu) and tRNA(Gln) and participates in RNA aminoacylation for mitochondrial protein translation. Attachs glutamate to tRNA(Glu) or tRNA(Gln) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) or tRNA(Gln). In vitro, cytoplasmic tRNA(Gln) is slightly glutamylated, but with low activity. 1. Nagao, A. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 16209-14. PMID: 19805282 | ||||||||
| 참고사항 | For research use only. |
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