Anti-EBV/HHV4 BMRF1 Polyclonal Antibody (VK074014)

Name: Anti-EBV/HHV4 BMRF1 Polyclonal Antibody
Brand: abinScience
SKU: VK074014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

VK074014

설명

Anti-EBV/HHV4 BMRF1 Polyclonal Antibody (VK074014) is a rabbit polyclonal antibody detecting DNA polymerase processivity factor BMRF1 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Epstein-Barr virus (HHV-4) (Human herpesvirus 4)

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant EBV/HHV4 BMRF1 (Met1-Ser314).

타겟

DNA polymerase processivity factor BMRF1, Early Antigen Diffused, EA-D, Polymerase accessory subunit

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P03191

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

DNA polymerase processivity factor BMRF1 is a ~43 kDa protein. Acts as a DNA polymerase processivity factor; a transcriptional activator for several EBV promoters and inhibits the host DNA damage response (DDR) to double-stranded DNA breaks. Plays an essential role in the viral lytic DNA replication by acting as a polymerase accessory subunit. Stimulates the viral DNA polymerase activity and appears to function with it as a holoenzyme. Increases the processivity of the viral polymerase, probably by acting as a sliding clamp that prevents dissociation of the polymerase from the active template. In addition, BMRF1 transcriptionally activates the oriLyt early BHLF1 promoter.

1. Neuhierl, B. et al. (2006) Journal of virology 80, 5078-81. PMID: 16641300

2. Murayama, K. et al. (2009) The Journal of biological chemistry 284, 35896-905. PMID: 19801550

3. Salamun, SG. et al. (2019) Journal of virology 93. PMID: 31462557

4. Zhang, Q. et al. (1996) Journal of virology 70, 5131-42. PMID: 8764021

5. Zhang, Q. et al. (1997) Virology 230, 22-34. PMID: 9126259

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-EBV/HHV4 BMRF1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-EBV/HHV4 BMRF1 Polyclonal Antibody (VK074014)

개요

이미지

참고 문헌

데이터시트

SDS

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