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| 카탈로그 번호 | HB164014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-EFNA1 Polyclonal Antibody (HB164014) is a rabbit polyclonal antibody detecting EFNA1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human EFNA1 (Asp19-Ser182). | ||||||||
| 타겟 | EPLG1, EFNA1, LERK1, Immediate early response protein B61, EPH-related receptor tyrosine kinase ligand 1, TNFAIP4, TNF alpha-induced protein 4, LERK-1, Ephrin-A1, Tumor necrosis factor alpha-induced protein 4 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P20827 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Ephrin-A1 (EFNA1) is a ~23 kDa protein. Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Involved in angiogenesis, regulating vascular endothelial cell differentiation and migration through activation of EPHA2. Acts as a ligand for EPHA3, inhibiting epithelial-to-mesenchymal transition of cardiac cells and playing a role in heart development. May also contribute to dendritic spine morphogenesis. 1. Liu, DP. et al. (2007) International journal of oncology 30, 865-71. PMID: 17332925 2. Wykosky, J. et al. (2008) Oncogene 27, 7260-73. PMID: 18794797 3. Sharfe, N. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 6024-32. PMID: 12794130 | ||||||||
| 참고사항 | For research use only. |
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