Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody (HB290014)

Name: Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody
Brand: abinScience
SKU: HB290014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HB290014

설명

Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody (HB290014) is a rabbit polyclonal antibody detecting Hu-antigen D in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Danio rerio, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human ELAVL4/HuD/Hu-antigen D (Val2-Ser380).

타겟

Paraneoplastic encephalomyelitis antigen HuD, HUD, Hu-antigen D, ELAVL4, PNEM, HuD, ELAV-like protein 4

정제

Purified by antigen affinity column.

등록번호

P26378

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

ELAV-like protein 4 (ELAVL4/HuD) is a ~42 kDa protein. RNA-binding protein that is involved in the post-transcriptional regulation of mRNAs. Plays a role in the regulation of mRNA stability, alternative splicing and translation. Binds to AU-rich element (ARE) sequences in the 3' untranslated region (UTR) of target mRNAs, including GAP43, VEGF, FOS, CDKN1A and ACHE mRNA. Many of the target mRNAs are coding for RNA-binding proteins, transcription factors and proteins involved in RNA processing and/or neuronal development and function. By binding to the mRNA 3'UTR, decreases mRNA deadenylation and thereby contributes to the stabilization of mRNA molecules and their protection from decay.

1. King, PH. (2000) Nucleic acids research 28, E20. PMID: 10710437

2. Beckel-Mitchener, AC. et al. (2002) The Journal of biological chemistry 277, 27996-8002. PMID: 12034726

3. Deschenes-Furry, J. et al. (2003) The Journal of biological chemistry 278, 5710-7. PMID: 12468554

4. Zhu, H. et al. (2006) Molecular biology of the cell 17, 5105-14. PMID: 17035636

5. Deschênes-Furry, J. et al. (2007) The Journal of neuroscience : the official journal of the Society for Neuroscience 27, 665-75. PMID: 17234598

6. Liu, J. et al. (1995) Neurology 45, 544-50. PMID: 7898713

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-ELAVL4/HuD/Hu-antigen D Polyclonal Antibody (HB290014)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기