Anti-EYA2 Polyclonal Antibody (HC008014)

Name: Anti-EYA2 Polyclonal Antibody
Brand: abinScience
SKU: HC008014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC008014

설명

Anti-EYA2 Polyclonal Antibody (HC008014) is a rabbit polyclonal antibody in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Chicken.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human EYA2 (Glu266-Leu538).

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O00167, Q58DB6, O08575, Q9YHA0

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Protein phosphatase EYA2 is a ~59 kDa protein. Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2; in this it is functionally redundant with EYA1.

1. Fougerousse, F. et al. (2002) Journal of muscle research and cell motility 23, 255-64. PMID: 12500905

2. Patrick, AN. et al. (2013) Nature structural & molecular biology 20, 447-53. PMID: 23435380

3. Krishnan, N. et al. (2009) The Journal of biological chemistry 284, 16066-16070. PMID: 19351884

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-EYA2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-EYA2 Polyclonal Antibody (HC008014)

개요

이미지

참고 문헌

데이터시트

SDS