Anti-FADS3 Polyclonal Antibody (HV205014)

Name: Anti-FADS3 Polyclonal Antibody
Brand: abinScience
SKU: HV205014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HV205014

설명

Anti-FADS3 Polyclonal Antibody (HV205014) is a rabbit polyclonal antibody detecting FADS3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human FADS3 (Glu331-Gln445).

타겟

Delta(13) fatty acid desaturase, Delta(13) desaturase, FADS3, Fatty acid desaturase 3, CYB5RP

정제

Purified by antigen affinity column.

등록번호

Q9Y5Q0

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Fatty acid desaturase 3 (FADS3) is a ~51 kDa protein. Mammals have different sphingoid bases that differ in their length and/or pattern of desaturation and hydroxyl groups. The predominant sphingoid base that comprises mammalian ceramides is sphing-4-enine (sphingosine or SPH) which has a trans (E) desaturation at carbon 4. FADS3 is a desaturase that introduces a cis (Z) double bond between carbon 14 and carbon 15 of the sphingoid base (also known as long chain base, LCB), producing LCBs such as sphinga-4,14-dienine (SPD, d18:2(4E,14Z)) from SPH. Prefers SPH-containing ceramides (N-acylsphing-4-enines) as substrates. Capable of metabolizing also the SPH in its free form.

1. Karsai, G. et al. (2020) The Journal of biological chemistry 295, 1889-1897. PMID: 31862735

2. Jojima, K. et al. (2020) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 34, 3318-3335. PMID: 31916624

3. Jojima, K. et al. (2023) Biochimica et biophysica acta. Molecular and cell biology of lipids 1868, 159335. PMID: 37209771

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-FADS3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-FADS3 Polyclonal Antibody (HV205014)

개요

이미지

참고 문헌

데이터시트

SDS