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| 카탈로그 번호 | HW309024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-FDFT1 Polyclonal Antibody (HW309024) is a rabbit polyclonal antibody detecting FDFT1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human FDFT1 (Met1-Gln283). | ||||||||
| 타겟 | Squalene synthase, Farnesyl-diphosphate farnesyltransferase 1, FDFT1, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P37268 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Squalene synthase (FDFT1) is a ~48 kDa protein. Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. | ||||||||
| 참고사항 | For research use only. |
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