Anti-FMO3 Polyclonal Antibody (HB603014)

Name: Anti-FMO3 Polyclonal Antibody
Brand: abinScience
SKU: HB603014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB603014

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human FMO3 (Lys280-Thr532).

타겟

Dimethylaniline oxidase 3, FMO form 2, Dimethylaniline monooxygenase [N-oxide-forming] 3, FMO3, FMO II, FMO 3, Trimethylamine monooxygenase, Hepatic flavin-containing monooxygenase 3

정제

Purified by antigen affinity column.

등록번호

P31513

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Flavin-containing monooxygenase 3 (FMO3) is a ~60 kDa protein. Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation.

1. Rawden, HC. et al. (2000) British journal of clinical pharmacology 49, 313-22. PMID: 10759686

2. Perez-Paramo, YX. et al. (2019) Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 28, 311-320. PMID: 30381441

3. Veeravalli, S. et al. (2020) Drug metabolism and disposition: the biological fate of chemicals 48, 378-385. PMID: 32156684

4. Lang, DH. et al. (1998) Biochemical pharmacology 56, 1005-12. PMID: 9776311

5. Zhu, W. et al. (2018) Journal of thrombosis and haemostasis : JTH 16, 1857-1872. PMID: 29981269

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-FMO3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-FMO3 Polyclonal Antibody (HB603014)

개요

이미지

참고 문헌

데이터시트

SDS

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