Anti-FUT2 Polyclonal Antibody (HC418014)

Name: Anti-FUT2 Polyclonal Antibody
Brand: abinScience
SKU: HC418014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HC418014

설명

Anti-FUT2 Polyclonal Antibody (HC418014) is a rabbit polyclonal antibody detecting FUT2 in ELISA, IHC, WB. Suitable for Human, Hylobates lar, Pan troglodytes, and Pongo pygmaeus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human FUT2 (Gln29-His343).

타겟

Fucosyltransferase 2, SE2, Se, Galactoside alpha-(1, 2)-fucosyltransferase 2, Secretor blood group alpha-2-fucosyltransferase, Alpha(1, 2)FT 2, Type 1 galactoside alpha-(1, 2)-fucosyltransferase FUT2, FUT2, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 2, Type 2 galactoside alpha-(1, 2)-fucosyltransferase FUT2, Secretor factor, SEC2

정제

Purified by antigen affinity column.

등록번호

Q10981

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Galactoside alpha-(1,2)-fucosyltransferase 2 (FUT2) is a ~39 kDa protein. Catalyzes the transfer of L-fucose, from a guanosine diphosphate-beta-L-fucose, to the terminal galactose on both O- and N-linked glycans chains of cell surface glycoproteins and glycolipids and the resulting epitope regulates several processes such as cell-cell interaction including host-microbe interaction, cell surface expression and cell proliferation. Preferentially fucosylates gangliosides GA1 and GM1 in the antrum, cecum and colon and in the female reproductive organs. Fucosylated host glycoproteins or glycolipids mediate interaction with intestinal microbiota influencing its composition. Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble ABO blood group antigen synthesis pathway.

1. Lindesmith, L. et al. (2003) Nature medicine 9, 548-53. PMID: 12692541

2. Kelly, RJ. et al. (1995) The Journal of biological chemistry 270, 4640-9. PMID: 7876235

3. Borén, T. et al. (1993) Science (New York, N.Y.) 262, 1892-5. PMID: 8018146

4. Wacklin, P. et al. (2011) PloS one 6, e20113. PMID: 21625510

5. Rausch, P. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 19030-5. PMID: 22068912

6. Wacklin, P. et al. (2014) PloS one 9, e94863. PMID: 24733310

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-FUT2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-FUT2 Polyclonal Antibody (HC418014)

개요

이미지

참고 문헌

데이터시트

SDS

빠른 접근

문의하기